Humulin R U-100 is short-acting and is often used in combination with intermediate- or long-acting insulins. There are also 50/50 and 70/30 compositions of both drugs available. HUMULIN R (insulin human injection, solution) comes in different strengths and amounts, which is referred to as the dosing of Humulin R . Do not change the insulin you use without talking to your doctor. HUMULIN (insulin, human biosynthetic) is indicated for the treatment of insulin requiring diabetic patients. Do not take this medicine if you have low blood sugar. Under no circumstances should any HUMULIN MIXTURE be given intravenously. Dosage & Administration. Instruct patients to always check the insulin label before each injection. In switching patients from animal source insulins to HUMULIN, it is possible that the patients will require a change in dosage; the adjustment may be made with the first dose or over a period of several weeks. Drug Monograph. Dosage/Direction for Use . An effective treat-to-target dosing algorithm with 2 or 3 injections of U-500 per day 1. In general, when an intermediate-acting insulin (e.g., NPH insulin isophane suspension) is mixed with short-acting soluble insulin (e.g., regular), the short-acting insulin should be drawn into the syringe first. Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Dosage Guidelines & Tips How to take Humulin R (Insulin Regular)? Carbohydrate counting and measuring your blood sugar levels before and after meals may help you determine an accurate dosage. The clinic If you use Humulin® R Concentrated U-500 insulin, be very careful when you measure the dose. (2.1) • Subcutaneous injection:injectsubcutaneously 30 minutes before a mealinto the thigh, upper arm, abdomen, or buttocks.Rotate injection sites to reduce risk of lipodystrophyand localized cutaneous amyloidosis. HUMULIN and HUMULIN MIXTURES should not be mixed with any other insulin unless clearly indicated and done under medical supervision (see DOSAGE AND ADMINISTRATION). A typical starting dosage for type 1 diabetes is about 0.5 units of Humulin R per kilogram of your body weight per day (1 kilogram is equal to about 2.2 pounds). Humulin R U-100 should not be used after the printed expiration date. The daily dose is usually divided in 2 to 3 doses and administered in varying ratios of NPH:regular insulin. Humulin R is one of several brands of "Regular" (short-acting) insulin, used for a quick consumption of blood sugar with little delay. Thus, in practice, Humulin R U-500 insulin is used as a basal insulin instead of a mealtime insulin. Never use Humulin R U-100 if it has become viscous (thickened) or cloudy; use it only if it is clear and colorless. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Inspect HUMULIN R U-500 visually for particulate matter and discoloration. Prescribe HUMULIN R U-500 ONLY to patients who require more than 200 units of insulin per day. Then there are Humulin N and Novolin N which are intermediate-acting. The pH is … Injection sites should be rotated within the same region. Only a U-500 insulin syringe should be used with Humulin R U-500 in order to avoid administration errors. For intravenous use, Humulin R U-100 should be used at concentrations from 0.1 unit/mL to 1 unit/mL in infusion systems with the infusion fluids 0.9% sodium chloride using polyvinyl chloride infusion bags. In switching patients from animal source insulins to HUMULIN, it is possible that the patients will require a change in dosage; the adjustment may be made with the first dose or over a period of several weeks. Click to view Humulin R detailed prescribing information Special Precautions Transferring to another type or brand, changes in strength, species, &/or method of manufacture of insulin, uncorrected hypoglycemic & hyperglycemic reactions, use of inadequate dosages, discontinuation of treatment, changes in food, activity or work schedule. These pre-filled KwikPens ® are also unlicensed in the UK and are imported from the USA via the same importer as the multidose vials. Train patients on proper use and injection technique before initiating HUMULIN R U-500. Follow the instructions that come with the pen. Changing insulin may lead to low or high blood sugar. There is no set Humulin R dosage that works for all people or for the same person in all situations. Humulin R Pen Body color: Beige Beige Dose Knob: Labels: White with Light Green Color Bar White with Yellow-Gold Color Bar Supplies needed to give your injection: • KwikPen containing your insulin • KwikPen compatible Needle (BD [Becton, Dickinson and Company] Pen Needles recommended) • Alcohol swab Preparing your Pen • Wash your hands with soap and water. Humulin R Dosage. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Available from: https://www.medicines.org.uk/emc/product/8193/smpc [Accessed August … Do not change the dose on the Humulin R insulin without consulting your doctor. Important Administration Instructions. How to Convert from U-100 Insulin to U-500 Insulin. Do not use Humulin R U-500 in an insulin pump or inject it into your vein or muscle. HUMULIN R U-500 is available as a single-patient-use KwikPen or multiple-dose vial. The dose window of the HUMULIN R U-500 KwikPen shows the number of units of HUMULIN R U-500 to be injected and NO dose conversion is required. Humulin R Dosage. Do not take this medicine if you have low blood sugar. Humulin R Cartridges Concentration and dose are not the same. However, in pre-pubertal children it usually varies from 0.7 to 1 unit/kg/day, but can be much lower during the period of partial remission. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Humulin KwikPen containing Humulin I formulation should be rolled in the palms of the hands ten times and inverted 180° ten times immediately before use to resuspend the insulin until it appears uniformly cloudy or milky. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. -Humulin(R): Dilute to a concentration of 0.1 to 1 unit/mL in an infusion system using polyvinyl chloride infusion bags; this insulin is stable in normal saline -Novolin(R): Dilute to a concentration of 0.05 to 1 unit/mL in an infusion system using polypropylene infusion bags; this insulin is stable in normal saline, 5% dextrose, or 10% dextrose with 40 mmol/L potassium chloride The appearance of Humulin R can differ based on the dosing. Clinicians must also determine that patients can draw up the correct insulin dosage before prescribing and dispensing. The concentration tells how many units of insulin are in each milliliter (mL). Dosage of human insulin, which is always expressed in USP units, must be based on the results of blood and urine glucose tests and must be carefully individualized to optimal effect. Do not use Humulin R U-500 in an insulin pump or inject it into your vein or muscle. The daily dose is usually divided in 2 to 3 doses and administered in varying ratios of NPH:regular insulin. What is the difference between regular insulin and lispro (Humalog)? Hey guys just had some thoughts on humlin r, I'm doing my first show and in between my last cycle and my pre contest and one of the guys I bounce info off was talking about humulin R for size gain before cutting down, 5 ius before meal 1 and 5 ius around 1 before another meal, any … Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. As with all insulin, the duration of action will vary according to the dose, injection site, blood flow, temperature, and level of physical activity. Changing insulin may lead to low or high blood sugar. It is available in: - Vials, 3 mL - Vials, 10 mL HUMULIN R is also available in: - Cartridges, 3 mL - KwikPens, 3 mL prefilled pen Other available HUMULIN products include HUMULIN N (NPH) and HUMULIN 30/70 (mixture of 30% Regular and 70% … Last updated on Nov 16, 2020. Initial: 0.2-0.4 units/kg/day SC divided q8hr or more frequently. Humulin R is one of several brands of "Regular" (short-acting) insulin, used for a quick consumption of blood sugar with little delay. The concentration tells how many units of insulin are in each milliliter (mL). Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Talk to your pharmacist for more details. HUMULIN-R onlyshould be used for the treatment of emergencies such as diabetic coma and pre-coma and in diabetics undergoing surgery, but notHUMULIN-N, or HUMULIN MIXTURES. Use only a U-500 insulin syringe with Humulin R U-500 to avoid administration errors. Prescribe HUMULIN R U-500 ONLY to patients who require more than 200 units of insulin per day. Dosing errors have occurred when the HUMULIN R U-500 dose was administered with syringes other than a U-500 insulin syringe. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The dose of Humulin R U-500 should always be expressed in units of insulin. Your doctor can recommend a Humulin R dosage based on the carbohydrate content of your meals. In situations of insulin resistance, e.g. Humulin R ® U500 insulin for ... intended dose to be dialled up in an identical manner to other insulin pens without needing to use a needle and syringe. Instruct patients to always check the insulin label before administration to confirm the correct insulin product is being used. If you do not use the right syringe, you may take the wrong dose of Humulin R U-500. Data sources include IBM Watson Micromedex (updated 1 Apr 2021), Cerner Multum™ (updated 5 Apr 2021), ASHP (updated 6 Apr 2021) and others. Individualize and titrate the dosage of HUMULIN R U-500 based on the patient's metabolic needs, blood glucose monitoring results, and glycemic control goal. The dosage and timing of Humulin R U-100 should be individualized and determined, based on the physician's advice, in accordance with the needs of the patient. during puberty or due to obesity, the daily insulin requirement may be substantially higher. HUMULIN R U-500 is available as a single-patient-use KwikPen or multiple-dose vial. Do not take this medicine if you have low blood sugar. U-100 insulins, including Humulin R, contain 100 units per mL. Humulin R U500 is a concentrated insulin that contains 5 times as many units of insulin per ml as U100. Maintain strict compliance with administration of Humulin R shot as ordered, with regards to dosage and frequency, to derive the benefit of the medication. With Humulin R, it is important to use a syringe that is marked for U-100 insulin preparations. Available for Android and iOS devices. HUMULIN R U-500 prescription and dosage sizes information for physicians and healthcare professionals. during puberty or due to obesity, the daily insulin requirement may be substantially higher. Confirm that the patient has understood these instructions and can correctly draw the prescribed dose of HUMULIN R U-500 with their syringe. HUMULIN N may be mixed with HUMULIN R or HUMALOG before injection. Humulin R. Generic Name: human insulin Dosage Form: injection, solution HUMULIN® R REGULAR INSULIN HUMAN INJECTION, USP (rDNA ORIGIN)100 UNITS PER ML (U-100) INFORMATION FOR THE PHYSICIAN HUMULIN® R REGULAR INSULIN HUMAN INJECTION, USP (rDNA ORIGIN) 100 UNITS PER ML (U-100) DESCRIPTION Humulin® R U-100 is a polypeptide hormone structurally identical to human … Push the bubbles out with the plunger and then withdraw the correct dose. Humulin R (insulin human recombinant) U-100 is a sterile, clear, aqueous, and colorless solution that contains human insulin (rDNA origin) 100 units/mL, glycerin 16 mg/mL and metacresol 2.5 mg/mL, endogenous zinc (approximately 0.015 mg/100 units) and water for injection. 10|11 A guide to starting Humulin® I Dose reduction is recommended if any results are consistently less than 4mmol/l (‘hypo’) at any time. Blood sugar patterns (>3 days) Humulin R is one of several brands of "Regular" (short-acting) insulin, used for a quick consumption of blood sugar with little delay. Individualize and adjust the dosage of HUMULIN R based on the route of administration, the patient's metabolic needs, blood glucose monitoring results, and glycemic control goal. Pharmacology, adverse reactions, warnings and side effects. There are 2 types of Humulin R insulin: Humulin R U-100 and a more concentrated insulin, Humulin R U-500. such as 100 units/mL (U-100), but this does not mean you will use 100 units at a time. Before removing the needle from the Humulin R bottle, check the syringe for air bubbles. DO NOT dilute or mix HUMULIN R U-500 with any other insulin products or solutions. Do not change the insulin you use without talking to your doctor. (2.1, 2.3, 2.4, 5.1) • HUMULIN R U-500 is available as a single-patient-use KwikPen or multiple-dose vial. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The dosage and timing of Humulin R U-100 should be individualized and determined, based on the physician's advice, in accordance with the needs of the patient. Detailed Information In a euglycemic clamp study of 24 healthy obese subject with a BMI of 30 to 39 kg/m 2 , single doses of SC U-500R at 50 units (0.4-0.6 units/kg) and 100 units (0.8-1.3 units/kg) resulted in a If bubbles are present, hold the syringe straight up and tap its side until the bubbles float to the top. Below are details on some common dosages for Humulin N, as well as ways the drug is commonly used. Humulin R U-100 should not be used after the printed expiration date. Do NOT perform dose conversion when using the Humulin R U-500 KwikPen or U-500 insulin syringe. how do I convert u500 to u100? The average range of total daily insulin requirement for maintenance therapy in insulin-treated patients without severe insulin resistance lies between 0.5 and 1 unit/kg/day. HUMULIN R given by subcutaneous injection should generally be used in regimens with an intermediate- or long-acting insulin. What is the difference between regular insulin and lispro (Humalog)? Subtract 10% to 20% from this sum to use for initial dosing. Failure to use the proper syringe can lead to a mistake in dosage, causing serious problems for you, such as … Initial suggested daily insulin requirements are roughly 0.3 to 0.7 units/kg/day; requirements usually increase during the second and third trimesters (i.e., 0.8 units/kg/day or more). Select one or more newsletters to continue. SC Dosage according to individual requirements. (Remember, Humulin R U-500 is only appropriate for patients who need more than 200 units of insulin/day). DO NOT perform dose conversion when using a U-500 insulin syringe. It consists of zinc insulin crystals dissolved in clear fluid with no additives to alter its action or speed2. Humulin R U-100 is a short-acting insulin, which means it can cover insulin needs for meals eaten within 30 minutes. Type 1 Diabetes Mellitus Suggested guidelines for beginning dose Ketones moderate or less: 0.5 U/kg/day SC Ketones large: 0.7 U/kg/day SC Typically, 50-75% of total daily dose is given as intermediate- or long-acting insulin May use this combination product if the dosage ratio of NPH (isophane) to regular is 2:1 Type 2 Diabetes Mellitus Suggested guidelines for beginning dose; adjust according to blood glucose levels Initial dose… such as 100 units/mL (U-100), but this does not mean you will use 100 units at a time. Humulin R U-100 may also be used in combination with oral antihyperglycemic agents or longer-acting insulin products to suit the needs of the individual patients with diabetes. There is currently no generic alternative for Humulin R, but less expensive biosimilar versions may be available in the future. Instruct patients using the vial presentation to use only a U-500 insulin syringe and on how to correctly draw the prescribed dose of HUMULIN R U-500 into the U-500 insulin syringe. 2 Other brands with the same action profile include: Novolin R 3 Humulin S 456 Huminsulin Normal Actrapid 789 Insuman Rapid 1011. HUMULIN R safely and effectively. The site of injection should be rotated within an area to avoid irritation and aid absorption. Take a blood sugar reading and make sure your blood sugars are not too low, when you are administering your Humulin R shot out of your regular scheduled time. The markings on the U-500 insulin syringe show the number of units of HUMULIN R U-500 to be injected. Initial dosages for patients with diabetes are often lower, e.g., 0.2 to 0.4 units/kg/day. Patients should be prescribed U-500 syringes for use with the HUMULIN R U-500 vials. Data sources include IBM Watson Micromedex (updated 1 Apr 2021), Cerner Multum™ (updated 5 Apr 2021), ASHP (updated 6 Apr 2021) and others. 5 WARNINGS AND PRECAUTIONS Dosage andAdministration (2.2) 11/2019 Warnings and Precautions(5.2) 11/2019-----INDICATIONS AND USAGE-----HUMULIN ® Ris ashort-actinghuman insulin indicated to improve glycemic control in adult and pediatric patientswith diabetes mellitus. Humulin R insulin regular. Do not change the dose on the Humulin R insulin without consulting your doctor. In situations of insulin resistance, e.g. Intravenous administration of Humulin R U-100 is possible under medical supervision with close monitoring of blood glucose and potassium levels to avoid hypoglycemia and hypokalemia. The dose is how many units of insulin you will use. HUMULIN® M3 (Mixture 3) 100IU/ml suspension for injection in vial. Making sure the tip of the needle is in the Humulin R solution, withdraw the correct dose of Humulin R into the syringe. Use HUMULIN R U-500 KwikPen with caution in patients with visual impairment that may rely on audible clicks to dial their dose. Medically reviewed by Drugs.com. We comply with the HONcode standard for trustworthy health information -. If you miss a dose, try taking it at the earliest notice of noncompliance. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Only use the U-500 insulin syringe to inject Humulin R U-500. 4 CONTRAINDICATIONS . a) Preparing a dose. The dose window of the HUMULIN R U-500 KwikPen shows the number of units of HUMULIN R U-500 to be injected and NO dose conversion is required. Dosage adjustments may be needed with changes in physical activity, changes in meal patterns (i.e., macronutrient content or timing of food intake), changes in renal or hepatic function, changes in medications or during acute illness to minimize the risk of hypoglycemia or hyperglycemia. It consists of zinc insulin crystals dissolved in clear fluid with no additives to alter its action or speed2. Common Brand(s): Humulin R Concentrated insulin regular is used with a proper diet and exercise program to control high blood sugar in people with diabetes who require large doses of insulin (more than 200 units per day). Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. See full prescribing information for HUMULIN R. HUMULIN R (insulin human injection), for subcutaneous or intravenous use . Changing insulin may lead to low or high blood sugar. Only use HUMULIN R U-500 if the solution appears clear and colorless. This eMedTV page lists other factors your doctor will consider when making a Humulin R dosing recommendation and offers tips for using this form of insulin. Do not use any other type of syringe to administer Humulin R U-500. • Humulin R U500 insulin is only available as a Kwikpen device. Instruct patients to inject HUMULIN R U-500 subcutaneously usually two or three times daily approximately 30 minutes before meals. -----DOSAGE AND ADMINISTRATION-----• Adhere to administration instructions to reduce the risk of dosing errors. You should use Humulin N according to your doctor’s instructions. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Patients using the vial must be prescribed the U-500 insulin syringe to avoid medication errors. However, in pre-pubertal children it usually varies from 0.7 to 1 unit/kg/day, but can be much lower during the period of partial remission. Initial suggested daily insulin requirements are roughly 0.3 to 0.7 units/kg/day; requirements usually increase during the second and third trimesters (i.e., 0.8 units/kg/day or more). Generic name: Insulin human 500[iU] in 1mLDosage form: injection, solution. You must only use Humulin S cartridges in Lilly insulin pens to ensure you get the correct dose. The average range of total daily insulin requirement for maintenance therapy in insulin-treated patients without severe insulin resistance lies between 0.5 and 1 unit/kg/day. Humulin R U-500 Kwikpen Dosage & Precautions Before using concentrated insulin regular, tell your doctor or pharmacist if you are allergic to it; or to other insulins; or if you have any other allergies. In-use vials must be used within 31 days or be discarded, even if they still contain Humulin R U-100. Injection into a lifted skin fold minimizes the risk of intramuscular injection. 2 Other brands with the same action profile include: Novolin R 3 Humulin S 456 Huminsulin Normal Actrapid 789 Insuman Rapid 1011. Do not use Humulin R U-100 after the expiration date stamped on the label or if it has been frozen. This form is more concentrated (has more medicine in the same amount of solution) than the U-100 form of insulin. When patients are transitioning from U-100 basal insulin to Humulin R U-500, it’s usually best to initially decrease the dose 10-20%. Adjust to achieve appropriate glucose control. Humulin N vs Humulin R - What's the difference? Instruct patients to inject HUMULIN R U-500 subcutaneously into the thigh, upper arm, abdomen, or buttocks. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. … The injection of Humulin R U-100 should be followed by a meal within approximately 30 minutes of administration. HUMULIN R is contraindicated: • during episodes of hypoglycemia • in patients with hypersensitivity to HUMULIN R or any of its excipients. HUMULIN ® Ris ashort ... -----DOSAGE AND ADMINISTRATION-----• See Full Prescribing Information for important administration instructions. Humulin R U-500 is usually administered 2 to 3 times daily approximately 30 minutes before meals. It consists of zinc insulin crystals dissolved in clear fluid with no additives to alter its action or speed. Generic name: insulin human U-100 insulin contains 100 units/mL (1 mL=1 cc). The daily dose is usually divided in 2—3 doses and administered in varying ratios of NPH: regular insulin. Inject immediately after mixing. Humulin R U-100 should only be mixed as directed by the physician. Change (rotate) your injection sites within the area you choose with each dose to reduce your risk of getting lipodystrophy (pits in skin or thickened skin) and localized cutaneous amyloidosis (skin with lumps) at the injection sites. Prescribe patients a U-500 insulin syringe to administer HUMULIN R U-500 from the vial to avoid administration errors. If Humulin R is mixed with Humulin N, Humulin R should be drawn into the syringe first. The order of mixing and brand or model of syringe should be specified by the physician. Humulin R is one of several brands of "Regular" (short-acting) insulin, used for a quick consumption of blood sugar with little delay. Humulin N, Humalog, metformin, Trulicity, Lantus, Victoza, Tresiba, Levemir, Novolog, Basaglar. Available for Android and iOS devices. Last updated on Nov 6, 2020. The dose is how many units of insulin you will use. Humulin® M3 can be injected into any of the places shown below. Medically reviewed by Drugs.com. We comply with the HONcode standard for trustworthy health information -. HUMULIN-R onlyshould be used for the treatment of emergencies such as diabetic coma and pre-coma and in diabetics undergoing surgery, but notHUMULIN-N, or HUMULIN MIXTURES. * Patients should check their blood glucose daily before each meal, at bedtime, and at 3 AM if they have increased their dose in the last 48 hours. There are Humulin R and Novolin R which are short-acting insulin. HUMULIN® R U-500 (insulin human injection): Dosage Schedule Humulin R U-500 is usually administered 2 to 3 times daily approximately 30 minutes before meals. When using the Humulin R U-500 vial: There is a special syringe to measure Humulin R U-500 called the "U-500 insulin syringe." Can regular and lispro insulin (Humalog) be mixed? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Special Precautions . Select one or more newsletters to continue. • Humulin R U500 insulin is a high strength insulin with 500 units/ml of insulin. What dosage forms it comes in: HUMULIN R (Regular) is a sterile solution containing insulin, human biosynthetic (rDNA origin) for injection. Humulin R U-100, when used subcutaneously, is usually given three or more times daily before meals. The HUMULIN R U-500 KwikPen dials in 5 unit increments. You will set the dose to 1 or 2 units. Talk to your pharmacist for more details. It is also dispensed in a 20 ml vial versus 10 ml for the U100. Dosing Considerations. Fasting (before breakfast) mmol/l Before evening meal mmol/l Before evening meal mmol/l adjust morning dose Night-time Humulin® I only Morning Humulin® I only Twice daily Humulin® I Night-time Humulin® I Use Humulin R (Insulin Regular) exactly as directed on the label, or as prescribed by your doctor. The prescribed dose of HUMULIN R U-500 should always be expressed in units of insulin [see Dosage and Administration (2.4)]. In-use (opened): The Humulin R U-100 vial currently in-use can be kept unrefrigerated as long as it is kept as cool as possible [below 30°C (86°F)] away from heat and light. This is actually a nice place to talk about practical ways to use Humulin R U-500 safely. Instructions for Mixing with Other Insulins HUMULIN N may be used with a prandial insulin if indicated. Then hold the pen with the needle pointing up and tap the side of the pen so that any bubbles float to the top. Humulin R Cartridges Concentration and dose are not the same. Humulin R is less popular than comparable drugs. Inject immediately after mixing. Admixture: Infusion bags prepared with Humulin R U-100 as indicated under DOSAGE AND ADMINISTRATION are stable when stored in a refrigerator (2° to 8°C [36° to 46°F]) for 48 hours and then may be used at room temperature for up to an additional 48 hours. Dosage guidelines are variable and must be individualized. Training reduces the risk of administration errors such as needle sticks and dosing errors. Dosage guidelines are variable and must be individualized. Put the cartridge into the pen. DO NOT perform dose conversion when using the HUMULIN R U-500 KwikPen. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Approximately 50-75% of the total daily insulin requirements are given as intermediate- or long-acting insulin administered in 1-2 injections; rapid- or short-acting insulin should be used … Other brands with the same action profile include: Novolin R3 Humulin S456 Actrapid789 Insuman Rapid1011 Humulin R (human insulin) is a short-acting type of insulin. HUMULIN R injection is 100 units per mL (U-100), a clear and colorless solution available as: • 10 mL multiple-dose vial • 3 mL multiple-dose vial . Subcutaneous injection into the abdominal wall ensures a faster absorption than from other injection sites. Do not change the insulin you use without talking to your doctor. It consists of zinc insulin crystals dissolved in clear fluid with no additives to alter its action or speed. A U-100 insulin syringe should always be used. Humulin N, Lyumjev, Humalog, metformin, Trulicity, Lantus, Victoza, Tresiba, sodium bicarbonate, Levemir. Patients using the vial must be prescribed the U-500 insulin syringe to avoid medication errors. Do not use Humulin R U-500 in an insulin pump or inject it into your vein or muscle. Click to view Humulin R detailed prescribing information ... Click to view Humulin R detailed prescribing information. It’s important to make sure you have the correct one. Humulin R U-100 may be administered by subcutaneous injection in the abdominal wall, the thigh, the gluteal region or in the upper arm. Humulin I KwikPen delivers up to 60 units per dose in single unit increments. Failure to use the correct syringe can lead to dosage errors. Do NOT perform dose conversion when using the Humulin R U-500 KwikPen or U-500 insulin syringe. Dosage adjustment may be needed when switching from another insulin to HUMULIN N [see Warnings and Precautions (5.2)]. You will need to use less of the solution for each dose.
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